Michael Hippler - Research Group
Physical Chemistry, University of Sheffield, England
Welcome to my research group webpage
I am a Senior Lecturer (equivalent to an Associate Professor) in Physical and Analytical Chemistry, University of Sheffield, England, with teaching in Physical and Analytical Chemistry and research interests to develop new laser spectroscopic techniques and to apply new laser sources for fundamental and analytical applications. I pursue analytical applications of laser spectroscopy, sensing and imaging in many collaborations with colleagues and industrial partners.
The aim of my research is the development of new methods and applications of ultra-sensitive laser spectroscopic techniques for analytical applications, including sensor applications of new light sources (DFB-QCL and diode lasers). During my research activities in Zürich and Sheffield I was able to develop new innovative experimental techniques for laser spectroscopy with great potential for analytical and fundamental applications.
Recent posts and links
- October 2021: Paper just accepted for publication in Analyst: 'Advanced Spectroscopic Analysis and 15N-Isotopic Labelling Study of Nitrate and Nitrite Reduction to Ammonia and Nitrous Oxide by E. coli ', G.D. Metcalfe, T.W. Smith and M. Hippler, Analyst, 2021, DOI: 10.1039/D1AN01261D. Thanks and congratulations to my co-authors! It describes the culmination of our analytical efforts and describes for the first time the combination of several advanced techniques, including CERS and White cell FTIR, and the simultaneous measurement of up to 20 different species and parameters in a relevant application, nitrate reduction by the model bacterium E. coli.
- August 2021: Paper just accepted for publication in Chemical Science: 'Tuning the Properties of Hydrogen-bonded Block Copolymer
Worm Gels Prepared via Polymerization-Induced Self-Assembly', E. Raphael, M. J. Berry, M. Hippler and S. P. Armes, Chem. Sci., 2021, 12, 12082-12091 (Impact 9.825) https://doi.org/10.1039/D1SC03156B - Analytical chemistry (spectroscopy) and ab initio calculations find many applications, here in polymer science!
- June 2021: Built a new Raman spectrometer with 532 nm excitation, based (modified, improved) on my publication 'Inexpensive Raman Spectrometer: J. Chem. Educ. 87 (2010), 326-330. DOI: 10.1021/ed800081t Go to J. Chem. Educ.'
- May 2021: The entire group is participating at the international Bunsenmeeting 2021; George Metcalfe is giving a talk 'Isotopically Labelling the Anaerobic Pathways of E. coli', Muneera AlRasheedi a poster 'Long-path FTIR and CERS Raman Analysis of Volatiles', Maryam Aldoghaim a poster 'Silver Nanospheres and Nanostars for SERS in the Biosciences', and Dr Hippler was re-elected as member of the steering committee (ständiger Ausschuss) of the German Bunsen Society for Physical Chemistry. Congratulations, Michael!
Go to presentations
- September 2020: My open access article Diode Laser Photoacoustic Spectroscopy in a Differential Helmholtz Resonator for Trace Gas Analysis in the Biosciences and Petrochemistry, Anal. Bioanal. Chem. (2019) 411:3777–3787, has been downloaded 1330 times! #myOAarticle https://link.springer.com/article/10.1007/s00216-019-01877-0.
- August 2020: 2 new publications just in print: Using activities to correct the Henderson-Hasselbalch equation, M. Hippler and G.D. Metcalfe, Bunsenmagazin, Vol. 22, Issue 5, 2020, 102-105. https://doi.org/10.26125/y7p7-an56
On-line Analysis and in situ pH Monitoring of Mixed Acid Fermentation by Escherichia coli using Combined FTIR and Raman Techniques, G.D. Metcalfe, T.W. Smith, and M. Hippler, Anal. Bioanal. Chem., 412(26) (2020) 7307-7319. https://doi.org/10.1007/s00216-020-02865-5
- February 2020: Maryam and Huw gave a presentation at a Florey Interdisciplinary Research Forum meeting at Sheffield University, presenting first results on 'Detecting and Probing of Microbes with Surface Enhanced Raman Spectroscopy (SERS) using Silver Nanoparticles'. See also the tweet, https://twitter.com/floreyinstitute/, and #floreyseminar.
- December 2019: Thanks to 'The Analytical Scientist' for writing a highlight article in their December 2019 issue on my cavity-enhanced Raman spectroscopy (CERS) technique as a promising new tool in biotech. Find the article here: https://theanalyticalscientist.com/
- 20/11/2019: We are branching into the field of Surface Enhanced Raman Spectroscopy (SERS) with silver nanoparticles, with Maryam Aldoghaim (PhD) and Huw Fletcher-Jones (MChem). We have succeeded in synthesizing nanoparticles and have obtained first SERS spectra of some interesting systems. More on this later ... Below TEM images of silver nanostars and nanospheres.
- 5/11/2019: We had to open the CERS optical cavity for cleaning. This allowed George Metcalfe (©) to take this picture, showing the power enhancement of the 635 nm diode laser inside the cavity.
- 18/9/2019: Visit to the Chatsworth estate in Derbyshire, England (https://www.chatsworth.org/) to harvest some bananas for scientific research. More on this soon ... (P.S.: the pictures were taken inside a greenhouse. This is not how Derbyshire looks like!)
- 16/9/2019: Cavity-Enhanced Raman and Helmholtz Resonator Photoacoustic Spectroscopy to Monitor the Mixed Sugar Metabolism of E. coli, by G. Metcalfe, S. Alahmari, T.W. Smith and M. Hippler has just been accepted by Analytical Chemistry, with very positive comments from the referees: '... exceptionally well written manuscript...', ' ...A frequent bottleneck in scientific instrumentation proposals for a specific analytical task is the lack of comparability... The present manuscript provides such detailed comparison between two powerful and still elegantly simple and cost-effective, non-sampling techniques...'
Go to Analytical Chemistry
- 30/5/2019: Dr Michael Hippler re-elected as member of the steering committee (ständiger Ausschuss) of the German Bunsen Society for Physical Chemistry, at the 118th General Assembly of the Society (Bunsentagung 2019) in Jena, Germany. Congratulations to myself ...
- 26/4/2019: Diode Laser Photoacoustic Spectroscopy in a Differential Helmholtz Resonator for Trace Gas Analysis in the Biosciences and Petrochemistry, by S. Alahmari (PhD student), X-W. Kang (MChem student) and M. Hippler has been accepted and selected as Paper in Forefront in Analytical & Bioanalytical Chemistry ! The Editor has recommended the manuscript for publication as a Paper in Forefront. The Editors select a number of exceptional papers for rapid publication as Papers in Forefront. These articles are given priority treatment, and they are printed prominently in a journal issue. (open access) Go to Analytical & Bioanalytical Chemistry
- March 2019: George Metcalfe (1st year PhD student) has won a generous bursary from the Association of British Spectroscopists to present a talk FTIR and Cavity-Enhanced Raman Spectroscopy for in situ, real-time Monitoring of Gases in the Biosciences at an international conference, Bunsentagung 2019 1st June 2019 in Jena, Germany. Congratulations, George!
- Cavity-Enhanced Raman Spectroscopy (CERS) in the Biosciences: Analytical Chemistry 89 (2017) 2147-2154. (open access) Go to Analytical Chemistry
- CERS of Natural Gas with Optical Feedback cw-Diode Lasers web link
- Journal Reference for CERS of Natural Gas: Analytical Chemistry 87 (2015) 7803-7809. (open access) Go to Analytical Chemistry
- Ultratrace Analytical Laser Spectroscopy for Humanitarian Demining, sponsored by the charity FABW youtube link
- Cavity-Enhanced Raman Spectroscopy (CERS): Analyst 137 (2012) 4669-4676. DOI: 10.1039/C2AN35722D Go to Analyst
- Inexpensive Raman Spectrometer: J. Chem. Educ. 87 (2010), 326-330. DOI: 10.1021/ed800081t Go to J. Chem. Educ.
- Quantum-chemical study and FTIR jet spectroscopy of CHCl3 - NH3 association in the gas phase: Phys. Chem. Chem. Phys. 12 (2010), 13555–13565. DOI: 10.1039/C0CP00530D Go to PCCP